Biologics are targeted, lab-made medications — usually given as injections or infusions — that block the specific immune signals driving inflammatory skin disease, rather than broadly suppressing the whole immune system.

In dermatology, biologics are used for moderate-to-severe plaque psoriasis, atopic dermatitis (eczema), and hidradenitis suppurativa, among other conditions. They are typically considered when topicals or phototherapy have not provided enough control.

Each biologic targets a specific cytokine or pathway — for example IL-17, IL-23, IL-4/IL-13, or TNF-α — to calm the overactive immune response that drives plaques, itching, and flares.

Most biologics are given as injections you can do at home after a quick training, while a few are IV infusions. Dosing schedules vary by medication, ranging from weekly to every several weeks.

Before starting, your provider usually screens for infections such as tuberculosis and hepatitis. Because biologics modulate the immune system, they can raise the risk of certain infections, so periodic check-ins and lab monitoring help keep treatment safe.

Biologics are specialty medications and almost always require insurance with prior authorization. Our team manages the prior-authorization paperwork and can connect eligible patients with manufacturer copay-assistance programs.

Biologics are generally for people with moderate-to-severe psoriasis, eczema, or hidradenitis suppurativa that has not responded to first-line treatments. Your provider will review your history and disease severity to confirm whether a biologic is appropriate.

Once your provider selects the right biologic, the prescription is sent to a specialty pharmacy and shipped to you, along with guidance on storage and self-injection.